Comparison of1H blood oxygen level-dependent (BOLD) and19F MRI to investigate tumor oxygenation
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چکیده
منابع مشابه
Blood oxygenation level-dependent MRI for assessment of renal oxygenation
Blood oxygen level-dependent magnetic resonance imaging (BOLD MRI) has recently emerged as an important noninvasive technique to assess intrarenal oxygenation under physiologic and pathophysiologic conditions. Although this tool represents a major addition to our armamentarium of methodologies to investigate the role of hypoxia in the pathogenesis of acute kidney injury and progressive chronic ...
متن کاملGenome Wide Association Study ) , BOLD ( Blood Oxygenation Level Dependent
Imaging genomics is a new field of investigation that seeks to gain insights into the impact of human genetic variation on the structure, chemistry and function of neural systems in health and disease. As publications in this field have increased over the past decade, increasing concerns have been raised about false positive results entering the literature. Here we provide an overview of the fi...
متن کاملMeasurement of renal tissue oxygenation with blood oxygen level-dependent MRI and oxygen transit modeling.
Blood oxygen level-dependent (BOLD) MRI data of kidney, while indicative of tissue oxygenation level (Po2), is in fact influenced by multiple confounding factors, such as R2, perfusion, oxygen permeability, and hematocrit. We aim to explore the feasibility of extracting tissue Po2 from renal BOLD data. A method of two steps was proposed: first, a Monte Carlo simulation to estimate blood oxygen ...
متن کاملIs T2* enough to assess oxygenation? Quantitative blood oxygen level-dependent analysis in brain tumor.
PURPOSE To analyze the contribution of the transverse relaxation parameter (T2), macroscopic field inhomogeneities (B0), and blood volume fraction (BVf) to blood oxygen level-dependent (BOLD)-based magnetic resonance (MR) measurements of blood oxygen saturation (SO2) obtained in a brain tumor model. MATERIALS AND METHODS This study was approved by the local committee for animal care and use. ...
متن کاملDetecting blood oxygen level-dependent (BOLD) contrast in the breast.
PURPOSE To develop a robust technique for detecting blood oxygenation level-dependent (BOLD) contrast in the human breast and to evaluate the signal in healthy and malignant breast. MATERIALS AND METHODS The design of this study focused on determining the optimal pulse sequence and stimulus for detecting BOLD contrast in the breast. For this study a single-shot fast spin echo (SSFSE) sequence...
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ژورنال
عنوان ژورنال: Magnetic Resonance in Medicine
سال: 2009
ISSN: 0740-3194,1522-2594
DOI: 10.1002/mrm.22020